Department of Clinical Pharmacology and Therapeutics, Clinical Trial Center, Dongguk University College of Medicine and Ilsan Hospital, Goyang, Korea. Department of Pharmacology, College of Medicine, Kangwon National University, Chuncheon, Korea. Department of Clinical Pharmacology and Toxicology, Korea University Guro Hospital, Seoul, Korea. Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea. Department of Clinical Pharmacology, Konkuk University Medical Center, Seoul, Korea.